膠原蛋白補充對骨骼、關節與肌肉的影響:最新研究解析

科學研究證實,補充水解膠原蛋白可能有助於減少關節疼痛、促進骨骼健康與增強肌肉恢復力。讓我們深入探討這些研究結果。 

根據 Brueckheimer PJ 等人 於 2025 年發表的系統性綜述,I 型水解膠原蛋白補充被研究為促進肌肉骨骼健康的潛在方法。這項研究彙整了現有文獻,發現膠原蛋白可能有助於改善骨骼密度、減少關節疼痛及增強肌肉修復能力。

研究重點:

想了解完整研究內容,可參閱原始文獻


Simental-Mendía M 等人 在 2025 年發表了一篇針對膠原蛋白補充與膝骨關節炎 (Osteoarthritis, OA) 關聯的系統性綜述與薈萃分析。這項研究分析了多項隨機對照試驗 (RCT),探討膠原蛋白對關節炎症狀的改善情況。

研究結果顯示:

完整研究內容請參考原始文獻


Khatri M 等人 於 2021 年發表的綜述研究中,科學家分析了膠原蛋白胜肽補充對身體組成、肌肉合成及運動恢復的影響。這篇研究從多個角度探討了膠原蛋白對運動員及一般人的潛在益處。

研究發現:

詳細研究可參閱原始文獻


除了膠原蛋白,許多其他膳食補充劑也被研究用於治療骨關節炎。根據 Liu X 等人 於 2018 年發表的薈萃分析,研究人員發現某些天然補充劑,如綠唇貽貝 (green-lipped mussel) 萃取物,可能對關節健康有幫助。

研究結論:

完整文獻請見原始研究


結論:膠原蛋白補充是否值得嘗試?

根據多項系統性綜述與薈萃分析,補充膠原蛋白可能對骨骼、關節與肌肉健康帶來正面影響,特別是在:
緩解關節炎症狀(如膝關節炎)
促進骨骼健康,降低骨質流失風險
改善運動恢復,減少肌肉酸痛

不過,個別效果仍可能因年齡、生活方式與劑量而異,建議有關節或骨骼問題的個人先諮詢專業醫療人員,再決定是否補充膠原蛋白。

如果你對這些研究有興趣,可以點擊每個標題進一步閱讀相關文獻,深入了解膠原蛋白的科學證據!💡



1

Cite Share

 

The Effects of Type I Collagen Hydrolysate Supplementation on Bones, Muscles, and Joints: A Systematic Review.

Brueckheimer PJ, Costa Silva T, Rodrigues L, Zague V, Isaia Filho C.

Orthop Rev (Pavia). 2025 Feb 19;17:129086. doi: 10.52965/001c.129086. eCollection 2025.

PMID: 39980497 Free PMC article.

The supplementation of type I hydrolyzed collagen has been investigated for its potential benefits in musculoskeletal health. OBJECTIVE: This systematic review aims to evaluate the current literature on the effects of type I hydrolyzed collagen

2

Cite Share

 

Effect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials.

Simental-Mendía M, Ortega-Mata D, Acosta-Olivo CA, Simental-Mendía LE, Peña-Martínez VM, Vilchez-Cavazos F.

Clin Exp Rheumatol. 2025 Jan;43(1):126-134. doi: 10.55563/clinexprheumatol/kflfr5. Epub 2024 Aug 20.

PMID: 39212129 Free article. Review.

OBJECTIVES: To perform a systematic review and meta-analysis to assess the clinical efficacy of collagen-based supplements on knee osteoarthritis (OA) symptoms. METHODS: Until October 2023, we conducted searches on the MEDLINE, EMBASE, Web of Science, …

3

Cite Share

 

The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review.

Khatri M, Naughton RJ, Clifford T, Harper LD, Corr L.

Amino Acids. 2021 Oct;53(10):1493-1506. doi: 10.1007/s00726-021-03072-x. Epub 2021 Sep 7.

PMID: 34491424 Free PMC article.

Study outcomes were categorised into four topics: (i) joint pain and recovery from joint injuries, (ii) body composition, (iii) muscle soreness and recovery from exercise, and (iv) muscle protein synthesis (MPS) and collagen synthesis. The results indi …

4

Cite Share

 

Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.

Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ.

Br J Sports Med. 2018 Feb;52(3):167-175. doi: 10.1136/bjsports-2016-097333. Epub 2017 Oct 10.

PMID: 29018060 Review.

OBJECTIVE: To investigate the efficacy and safety of dietary supplements for patients with osteoarthritis. DESIGN: An intervention systematic review with random effects meta-analysis and meta-regression. ...Only green-lipped mussel extract and u …